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The human trial results were mixed
Granneman JG et al
The relative abundance of the [ Eubacterium ] coprostanoligenes group was greater in both the vehicle- and 5A-1MQ-treated groups switched from WD to LD compared to the LD control group (Supplementary Fig
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However, it is imperative to note that findings from animal models cannot be directly extrapolated to clinical trials in humans
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