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After the inflammatory complex activation of NLRP3, Caspase-1 is markedly activated by the NLRP3 complex to form active Caspase-1
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Patient Population Patients were assigned to either cohort 1 or 2
We use DEXA scans to track your actual body compositionverifying you're losing fat while preserving muscle
In total, 5 mice in the normal group did not reach this threshold (as expected), while all 25 mice in the other groups reached this threshold
There may be a short window (one or two hours) to prevent more damage
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