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MT-1s MC1R-preferential activity makes it the primary research tool for studying MC1R biology in pigmentation, photoprotection, and skin immunology without the confounding central melanocortin receptor activation that limits the interpretability of studies using less selective melanocortin agonists
On the other hand, the icv administration of GLP-2 to mice and rats produced a marked decrease in food intake but not in water ingestion [43]
We thank the Cloning, Cell Expression and Protein Purification Core Facilities of iHuman Institute for their support
PMID 20599753
Refer to the below section for medications prescribed by Calibrate clinicians
Table 2 Parameter estimates of final model and 95% confidential interval
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