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They work through related but different mechanisms, they have different efficacy profiles in the data, and they behave differently in different people
Its a weight not only off their frame, but for many, their mind, too
Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease
Because the two share overlapping repair pathways, isolating the effect of the combination is also difficult to design cleanly
More studies need to be done to know for sure though
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