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doi: 10.1016/j.lfs.2016.02.029
N.ShirleyR.McClureJ
However, it is now believed that while cell senescence initially acts as a robust barrier against tumor initiation, the subsequent accumulation of senescent cells can paradoxically promote cancer recurrence and cause damage to neighboring tissues
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This raising of GFR is also seen with glucagon agonists and is under investigation right now in multiple clinical trials
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