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Nature 199 , 784787 (1963)
Glutathione is a fragile molecule, and most of what's in a standard capsule gets broken down in your digestive tract before reaching your cells
Therefore, targeting cellular oxidative stress through antioxidants has been suggested as a potential therapeutic option against neurological disorders, particularly using natural plant extracts
5-Amino-1MQ instead removes a drain on that route: by inhibiting NNMT it prevents nicotinamide from being methylated to 1-methylnicotinamide, leaving it available for NAMPT and the salvage pathway, and simultaneously spares the S-adenosyl-L-methionine that the methylation would have consumed
Further randomized clinical trials are required to validate these findings in human populations
BPC-157 has been administered intraperitoneally and intragastrically in animal models
