This effect is often the desired outcome for those taking this medication, yet additional considerations exist in practice and warrant clinical management
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
Track your pen, your dose level, and your injection site so you always know exactly where you are in your treatment
Other Health Risks to Watch For Pancreatitis (pancreas swelling): There were early worries about this, but big studies show that GLP1 drugs do not raise the risk for most people
206 YeN.ZhuG.LiuY.ZhangA.LiY.LiuR.et al
University of Wisconsin Press