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doi: 10.21037/atm-21-1595 17 NamgaladzeDFuhrmannDCBrneB

What's the difference between the two

GSH is regenerated from GS-TNB by glutathione reductase and will again react with DTNB to produce TNB

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Although biochemically separated from the GSH system, the Trx system shares NADPH as a common reducing cofactor and serves as an alternative pathway for reducing disulfide bonds, making this system especially relevant if the GSH system has been compromised or rendered dysfunctional (Silva-Adaya et al., 2014)

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