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These investigations provide valuable insight into growth hormone fragment biology and peptide-mediated cellular communication
Related reading: toxic overload, elevated SAH and impaired methylation
Curated affinity data instead describe a full agonist at four of the five human melanocortin receptors: reported pIC 10.0 at MC1R, pKi 8.9 at MC3R, pKi 8.5 to 8.8 at MC4R, and pIC 9.0 at MC5R, with no activity at MC2R, the adrenocorticotropin receptor, which is not engaged by alpha-MSH analogues of this class
doi: 10.1111/j.1365-2567.2011.03506.x 43 YustaBBaggioLLKoehlerJHollandDCaoXPinnellLJet al
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