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CrossRef Elevated adipose inflammation, but reduced hepatic triacylglycerol storage in diet-induced obese Plin4/ mice Atanaska Ivanova Doncheva, Ryoko Higa, Prabhat Khanal, Martine Villemo ksenvg Ingebrigtsen, Yuchuan Li, Shrikant Kolan, Pratibha Kolan, Ales Kvasnicka, Ingunn Jermstad, Shaista Khan, Bjrn Steen Sklhegg, Svein Olav Kolset, Hilde Nebb, Marit Hjorth, Fro Journal of Biological Chemistry .2026

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Even though they can be commercially acquired as a cell line, being readily characterized and accessible, one disadvantage lies in the fact that they may not express all the surface molecules as primary cells do, due to the immortalization process, making them a less reliable model of the in vivo behavior [88]