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Origin, chemistry, physiology, and pathophysiology of the gastrointestinal hormones
doi: 10.3389/fimmu.2023.1148209 Received 19 January 2023 Accepted 26 April 2023 Published 17 May 2023 Volume 14 - 2023 Edited by Christoph Thiemermann, Queen Mary University of London, United Kingdom Reviewed by Marcin Filip Osuchowski, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Austria
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This confirms that the observed metabolic reprogramming was dependent on chronic activation of GLP-1R signalling and independent of its acute stimulation of insulin secretion, which may result in autocrine insulin signalling
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