By the third day, they have a Herxheimer kind of reaction
What happens if I add more bacteriostatic water
Andrade JC, Almeida D, Domingos M, Seabra CL, Machado D, Freitas AC, et al
For comparison, tirzepatide (Mounjaro, Zepbound) has a slightly lower constipation rate at 14-17% across doses, possibly because the GIP receptor component partially counteracts GLP-1's motility effects in some patients
Clinical Benefits Beyond Blood Sugar Control The potential anti-inflammatory properties of GLP-1 receptor agonists may contribute to their demonstrated cardiovascular and renal benefits , which have been observed in large-scale cardiovascular outcome trials