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Inositol Inositol, usually considered a member of the vitamin B family, is produced by the body itself and is therefore not considered a vitamin
Common applications include: Cisplatin nephrotoxicity model : Inducing oxidative stress and proximal tubule injury in organoids to study antioxidant treatment strategies ( Vancomycin and statin toxicity : Assessing drug-induced mitochondrial dysfunction and reabsorption impairment ( Reperfusion injury and hypoxia models : Combining hypoxic culture with ROS stimulation to simulate the complex mechanisms of AKI onset in clinical settings ( Additionally, the degree of injury and recovery can be dynamically assessed using marker expression (such as KIM-1, NGAL) and functional indicators (glucose uptake, electrolyte transport) ( 2.3.3 Preliminary exploration of chronic kidney disease and fibrosis models CKD is often accompanied by persistent inflammation and renal interstitial fibrosis
