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GRX-Based Selective Reduction and Enrichment This chemical approach involves the following steps: Free thiols are first blocked using N-ethylmaleimide (NEM)

doi:10.3390/ijms19071987

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Critically, supersulfides, such as glutathione persulphide (GSSH), directly scavenge ferroptosis-implicated free radicals, notably LOO, via rapid hydrogen-atom transfer [224], while concurrently suppressing key ferroptotic drivers including inflammatory cytokines [225] and lipid peroxidation end-products (4-HNE) [226]