how to inject semaglutide in thigh Where Ozempic: Stomach, Arm, or Thigh? How to Inject Semaglutide in

10.1126/sciadv.1701028 21 Serrano-LotinaA.PortelaR.BaezaP.Alcolea-RodriguezV.VillarroelM.vilaP

Hormones & Signaling GLP-1: released after eating Insulin: blood sugar regulation Glucagon: raises blood sugar when it drops Oxytocin: bonding, labor, social behavior Vasopressin: blood pressure and water retention Pain & Mood Endorphins: your natural painkillers, released during exercise Enkephalins: pain modulation throughout the nervous system Dynorphins: stress response and pain regulation Immune Defense Defensins: antimicrobial peptides that attack bacteria, fungi, and viruses Cathelicidins: front-line immune response in skin and lungs Digestion Cholecystokinin (CCK): signals fullness after eating Ghrelin: the hunger hormone, signals when you need to eat Secretin: regulates stomach acid and pancreatic function Cardiovascular BNP (B-type natriuretic peptide): regulates blood pressure

At doses above 20mg, many users report pronounced perspiration during and after workouts

Exendin-4 Stimulates Islet Cell Replication via the IGF1 Receptor Activation of Mtorc1/S6K1

A good provider monitors your response and decides whether to continue escalating or hold at this dose

Band intensities were quantitated by densitometry