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[1] Important safety considerations include the risk of hypoglycaemia when combined with insulin or sulfonylureas, potential dehydration and acute kidney injury with severe gastrointestinal symptoms, and for semaglutide specifically, possible worsening of diabetic retinopathy in those with pre-existing disease

Its also important to share all medications and supplements youre currently taking, as some may interact or require adjustment

221,222 Ischemic necrosis of myocardial tissue triggers biomechanical changes during cardiac contraction and relaxation, which activate myofibroblasts to produce excessive collagen

[1] [4] Whilst these medications are generally well-tolerated and effective, patients and healthcare professionals have raised concerns about potential effects on mood and emotional wellbeing

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