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in Clinical Pharmacology & Therapeutics found subcutaneous injection reached peak plasma concentration (Tmax) at 75 minutes versus 38 minutes for IM, but area-under-curve (total bioavailability) was statistically equivalent at 94% versus 97%

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A 15 to 25% rise above baseline confirms adequate GH stimulation

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Hepatocytes have no or very low levels of GLP-1R, and studies report no direct effects of GLP-1R agonist on hepatocytes 11