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In the M-ARCOL model (Mucosal Artificial Colon, an advanced in vitro system using microbiota from healthy donors), daily exposure to PEMPs for 14 days increased pathobiont Desulfovibrionaceae (Fournier et al., 2023)

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Compared with traditional drugs that block signaling pathways 8 , chimeric antigen receptor (CAR)-T therapy has shown promising prospects for the treatment of fibrosis 9

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IGF-1 LR3 shows modest lipolytic effects in cell studies but minimal direct fat loss in whole organisms