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Several other molecules/companies are seeking licensing approval for obesity, noticeably tirzepatide (Mounjaro by Eli Lilly), a combined GLP-1 and GIP (Glucose-dependent Insulinotropic Polypeptide) agonist, both of which stimulate insulin secretion
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This produces severe nausea, vomiting, and occasionally ER visits for dehydration
Conclusion GLP-1 receptor agonists have emerged as groundbreaking therapeutic options for NASH patients, addressing a critical unmet need in hepatology
2004 A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells
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