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Individuals with AVED have a mutation in their alpha-TTP that prevents it from functioning correctly

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NDI1 expression led to increased NAD + , nucleotides and -ketoglutarate with reduced succinate

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The progressive ramp through the cycle is intentional: it allows the body to respond to the compound gradually, lets the provider assess tolerance and response before increasing the dose, and avoids the unnecessary load of starting at maximum dosing when the tissue is still in early repair phases

How long do the benefits of IV therapy last