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The human mtRNAP conducts a higher efficiency of NAD + capping than the nuclear RNAP II, leading to ~15% NAD + capping of mitochondrial transcripts

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At MC4R, expressed in the paraventricular nucleus and other CNS regions, MT-2 activates pathways involved in sexual arousal and erectile function researchers observed that MC4R signaling stimulates oxytocinergic neurons that project to spinal centers controlling erectile tissue

These numbers are significant