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659 The level of GPX4 in the brain gradually decreases after TBI, and overexpression of GPX4 can partially reverse TBI-induced hippocampal ferroptosis and synaptic damage, effectively alleviating neuronal dysfunction after cerebral hemorrhage, and improving TBI-induced cognitive deficits

Glucagon-like peptide-1 (GLP-1) is a hormone your body naturally produces in the gut

And with a tolerability profile observed to date in line with a routine upper endoscopy, this is the kind of durable, procedure-based approach I could see fitting naturally into how we care for these patients. GLP-1 medicines have transformed obesity care, but they were never designed to be taken forever, and the field's answer so far has been to keep patients on a drug indefinitely

Quality and Sourcing As with any injectable peptide, sourcing matters enormously

No subject experienced side effects related to hypoglycaemia and HbA1c levels were unaffected