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Brand-name list prices run roughly $1,000 to $1,350 per month for both Wegovy and Zepbound, though Eli Lilly's LillyDirect direct-pay vials for Zepbound have brought entry doses closer to $349 to $499 per month

However, you should still inform your GP as both medications can cause overlapping side effects that require monitoring

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Continuous daily use is not recommended, particularly for those with a cancer history

Several Phase 3 trials cover type 2 diabetes (TRANSCEND-T2D), obstructive sleep apnea, MASLD, chronic kidney disease in patients with type 2 diabetes, knee osteoarthritis (TRIUMPH-4), and cardiovascular outcomes

Conversely, some patients report temporary digestive changes as their system readjusts to the absence of the medication