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It won't dissolve properly in plain bacteriostatic water and will cloud, flake, or gel at the bottom of the vial instead
Clinical pharmacokinetics of epoetin (recombinant human erythropoietin)
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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations
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