In contrast to EAE where the primary stimulus is immune upregulation in the presence of extrinsic myelin antigens, the CAE model illustrates that MS-like pathology can also be generated by an upstream intrinsic myelin injury, releasing antigens which secondarily trigger white matter inflammation in an immune-predisposed host
Lefebvre-Demers M, Doyon N, Fecteau S
(Cell Tissue Res, 2019), and Klicek et al
Treatment for vitamin B12 shortage brought on by an absorption issue includes intramuscular injection in the event of Biermer's illness, Imerslund's disease, or stomach or intestinal ablation
In this Huberman Lab Essentials episode, he walks through his big six lifestyle pillars and explains why men are scared to talk about their testosterone levels, while women have way more objective data to work with
Fat-Soluble Vitamins There are two types of vitamins: water-soluble and fat-soluble