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The GLP-1 receptor agonist, exendin-4, has a longer duration of action, and has recently been approved as a new agent for the treatment of type 2 diabetes mellitus
Though several molecules, such as mazdutide, a GLP/glucagon dual agonist, are being studied in various phases, the first agent targeting incretins other than just GLP-1 was approved in 2022 tirzepatide [41]
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Studies show that nausea affects 14-28% of people taking GLP-1 medications
While this doesnt necessarily make Amoxicillin less effective overall, it could delay the onset of its action or alter its peak concentration, which might be a consideration for certain infections
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