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This meant that GLP-1RA could not only indirectly mediate M2 polarization of microglia by regulating Tregs, but also directly bind to GLP-1R on the membrane surface of microglia, completing M2 polarization through the GLP-1R/cAMP/PKA/IL-10 signaling pathway ( Recent research showed that GLP-1RA could reduce plasma TNF- levels induced by different Toll-like receptor agonists and significantly inhibit neuroinflammation (98)
These findings support the exploration of polyphenols not only in stroke prevention but also as adjuncts to enhance post-stroke recovery
How GLP-1s work and why theyre effective
Decide if you want daytime protection (morning) or nighttime repair (evening)
( Epub 20180402 )
Blood clots are semi-solid lumps of blood cells stuck together
