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Insulin dose per kilogram as a practical proxy for insulin resistance in T1D (reference bands)

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Alimentary Pharmacology & Therapeutics, 17 (4), 595-601

While selective activation of PPAR by fibric acid derivates (fibrates) primarily improves hepatic lipid and cholesterol metabolism 3 , the selective activation of PPAR by thiazolidinediones (TZDs) enhances insulin sensitivity in peripheral tissues such as the adipose tissue, liver and skeletal muscle 4

Laboratory or animal findings can identify mechanisms worth studying, but they do not prove patient benefit