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Retatrutide is an investigational medication currently being developed by Eli Lilly for the treatment of obesity and overweight

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Vrang N, Jelsing J, Simonsen L, Jensen AE, Thorup I, Soeborg H, and Knudsen LB

So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets

All authentic sellers label it for research use only. Its reputation comes from strong preclinical (animal/lab) evidence, not any large-scale human clinical trials