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Because these conditions prevent adequate oral uptake, intramuscular injection bypasses the digestive system entirely and delivers B12 directly into muscle tissue for reliable absorption
- [Stability of Reconstituted Peptide Formulations Under Refrigerated Storage]( *International Journal of Pharmaceutical Compounding*, 2023
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It's a single-use option, so it isn't meant for vials you'll draw from repeatedly.
Standard UK treatment involves hydroxocobalamin 1 mg intramuscular injections three times weekly for 2 weeks, then every 3 months lifelong for patients without neurological involvement
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