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A key point for interpretation is that cell migration and cell proliferation are related but not identical
PMID: 29597082
Smoking causes a great deal of oxidative stress which depletes glutathione
Reduction of the SASP Inflammatory Cascade The Senescence-Associated Secretory Phenotype (SASP) involves the secretion of pro-inflammatory cytokines, growth factors, and proteases that damage neighboring cells
High mobility group box 1 (HMGB1): HMGB1 is a nuclear protein that plays essential roles within the cell, such as organizing genetic material and facilitating DNA repair
Individual outcomes cannot be guaranteed, and patient responses vary
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