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Semaglutide activates (an agonist) the GLP-1 receptor, while tirzepatide is in a new class of dual agonists: it activates (mimics) both the GLP-1 receptor and GIP receptors (Gastric inhibit polypeptide is also known as glucose-dependent insulinotropic polypeptide.) The potency of activation for tirzepatide is 5-fold more for GIPR than GLP1
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Part V: The Regulatory Exclusivity Stack Two Systems, One Commercial Runway Patent protection and regulatory exclusivity are legally independent systems that operate in parallel
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doi: 10.1038/s41588-022-01091-2 54 SunLZhangYYangBSunSZhangPLuoZet al
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