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Notably, since the expression levels of the transferrin receptor (TfR) along with the TfR-dependent internalization mechanisms are still preserved and not affected in brain capillary endothelial cells of both mouse models of AD and human patients, TfR particularly represents an appealing target for NP-mediated drug delivery strategies (Bourassa et al., 2019)
Excessive activation of Notch signaling in macrophages promote kidney inflammation, fibrosis, and necroptosis
Furthermore, the applicability of our findings might be limited, because the NMA was based on indirect comparisons but not direct comparisons
Combining exercise and dietary changes has a multiplicative effect on weight loss with a similar trend in lipids
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