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Underlying conditions: Diabetes, thyroid disorders, and other hormonal conditions require careful monitoring during therapy

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It is also well known that physical activity can increase the diversity of intestinal microbiota, enhance SCFA production and stimulate anti-inflammatory mechanisms, mainly aerobic exercises, such as running, cycling, fitness exercises [86, 156, 157]

for neutral grounding on indications and biology, see Vitamin B12 Health Professional Fact Sheet , which outlines deficiency care and dosing context for clinicians

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