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All findings described are from in-vitro or animal research.

Here is what happens when NNMT is overactive: Your cells store more fat and burn less energy NAD+ levels drop (a critical molecule for energy production and cellular health) Insulin sensitivity decreases (making it harder to control blood sugar) Inflammation increases in fat tissue Metabolism slows down According to research in PMC, NNMT expression is upregulated in the white adipose tissue of obese and diabetic mice

In early studies, this leads to better energy utilization and potentially more significant fat loss than whats been documented with AOD9604 (review)

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For individuals experiencing chronic fatigue or low energy, evaluating B12 deficiency can be a crucial step