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While all three compounds stimulate growth hormone release via the GHS-R1a receptor, preclinical data from Raun et al
The widespread distribution of GLP-1 receptors means that activating them produces ripple effects across multiple organ systems, and each new study reveals additional potential applications
Tirzepatide is the next-generation GLP-1 drug a dual-action peptide that targets both GLP-1 and GIP receptors and produces meaningfully greater weight loss than semaglutide in head-to-head trials
Bmj 339 , b2535, (2009)
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