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The drug activates THR, a nuclear hormone receptor predominantly expressed in the liver and acts as a key regulator of metabolic pathways in this organ
The negative growth inhibition control (0.5% (v/v) DMSO) slightly impaired parasite growth (Naidu et al., 2018), more so than the lowest concentrations of drugs tested, therefore at very low drug concentrations the IC 50 curves exhibit negative values ( Figure 5 )
Without effective and timely interventions, prediabetes, which is the pre-stage of overt diabetes, can result in diabetes
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About this article Cite this article Maran, G., Muoz-Escassi, B., Manley, W
Bidirectional relationship between epigenetic age and stroke, dementia, and late-life depression
