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Novel Resveratrol-Based Aspirin Prodrugs: synthesis, Metabolism, and Anticancer Activity

Glitazones, the major PPAR-agonist, decreases glucose but not TGs

Pregnancy and breastfeeding are clear contraindications - we lack sufficient safety data on high-dose IV administration during these times

So far, can be used for obesity, type 2 diabetes, cardiovascular risk, and obstructive sleep apnea

It works by signaling the pituitary gland to release growth hormone over time , creating a steady and sustainable effect

In this Review, we highlight the latest advances in our understanding of the mechanisms of action of metformin and discuss potential emerging novel therapeutic uses