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By 1997, Ng and colleagues had identified the C-terminal segment of human GH as the primary region governing fat metabolism, and created AOD 9604 by adding a tyrosine residue to the fragment to enhance its stability
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Adipocyte hypertrophy is associated with increased uptake of excess TAGs, which triggers fat accumulation within the larger subcutaneous adipose tissue (SAT) [18, 19, 20]
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