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Most patients complete the immunotherapy program in three to five years

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Preclinical and early clinical studies support the potential of these approaches to improve early AD detection and enhance the safety and efficacy of therapeutic interventions, thereby paving the way for breakthroughs in personalized neurodegenerative medicine [108, 131, 132]

doi:10.1007/s10815-021-02247-5

Overall, the benefit-risk profile supports broad use of GLP-1-based therapies in MASLD across most patient subgroups, with individualized monitoring plans for high-risk populations

Across studies, these models yield an average AUC value of ~ 0.700.75, indicating a substantial but not conclusive illness signal