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Collectively, these results highlight the neuroprotective effects of GO@GSH-FA, demonstrating its potential to mitigate neurological deficits and improve neurocognitive outcomes in an in vivo model of cerebral Ischemia-Reperfusion injury
As a marker for host cell cytotoxicity, the activity of the ubiquitous cytoplasmic enzyme lactate dehydrogenase (LDH) was quantified in supernatants of infected A-431 cells after 18 and 45 hpi using a Cytotoxicity Detection Kit (Roche) according to the manufacturers protocol
The use of oral or topical glutathione depends on the requirements and advice of healthcare professionals
Glutathione metabolism and the novel role of mitochondrial GSH in retinal degeneration
Antioxidants 13(3):254 Massa CM, Liu Z, Taylor S, Pettit AP, Stakheyeva MN, Korotkova E, Popova V, Atochina-Vasserman EN, Gow AJ (2021) Biological mechanisms of s-nitrosothiol formation and degradation: how is specificity of s-nitrosylation achieved