What is AOD 9604
The mechanism by which GLP-1 receptor agonists might contribute to pancreatitis risk remains unclear, but possibilities include effects on pancreatic enzyme secretion, changes in gallbladder motility leading to gallstone formation, or direct effects on pancreatic tissue
It modulates over 4,000 genes involved in tissue remodeling, suppresses pro-inflammatory cytokines (IL-6, TNF-alpha), and activates proteasome and antioxidant pathways (Pickart et al., BioMed Res Int, 2012)
Large human trials and better active surveillance would help answer these questions
While GHK-Cu is a well-researched topical ingredient, injectable GHK-Cu peptides are neither FDA approved nor regulated and aren't recommended
Newer compounds like DHHB are also gaining attention in functional medicine for neuroprotection