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Regulatory Investigations In July 2023, the Icelandic Medicines Agency received reports about suicidal ideation in patients using GLP-1s, and the European Medicines Agency (EMA) initiated a review of a possible association between GLP-1 usage and suicidal ideation
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Consequently, further investigation is warranted [29]
A 2022 review in Diabetes, Obesity and Metabolism found that individuals who discontinued semaglutide regained approximately two-thirds of their lost weight within a year (Wilding et al., 2022)
GLP-1 receptor agonist use is associated with a reduced risk of developing rheumatoid arthritis in the first place
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