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At baseline, the average age of the patients was 38.94 14.55, the average BHB level was 0.16 0.08 mmol/L (negative, as expected prior to starting MAD), the average fasting triglyceride level was 102.95 76.03, average body weight was 80.5 23.18 kg, and average number of seizures per week was 2.68 3.15
Furthermore, metformin treatment markedly inhibits mitochondrial injuries and the expression of proteins and genes associated with ferroptosis in cardiomyocytes and neurons [35, 36]
Apart from this, the authors declare no conflict of interest
The entire purpose of a control group is to isolate the supplement's effect from the natural effects of being in a study, receiving attention, and knowing your weight is being tracked
