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Dual-pronged attack: pH-driven membrane-anchored NIR dual-type nano-photosensitizer excites immunogenic pyroptosis and sequester immune checkpoint for enhanced prostate cancer photo-immunotherapy
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319 Furthermore, CAF-derived IGF-1 activates the IGF1R/Akt/mTOR/c-Myc pathway to upregulate QSOX2, reinforcing CSC phenotypes and therapy resistance
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