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Diagnostic biomarkers for B12 status include decreased levels of circulating total B12 and transcobalamin-bound B12, and abnormally increased levels of homocysteine and methylmalonic acid
Take on an empty stomach - 30 minutes before or 2 hours after food
Patient reports do not consistently show this pattern
Proteins were separated by sodium dodecyl sulfate polyacrylamide gel electrophoresis and transferred to polyvinylidene difluoride membranes (Millipore, Bedford, MA, USA)
There is no direct treatment for high vitamin B12 because the elevated level itself is not a disease
Some might need B12 shots for life to keep their levels up
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