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The speed of improvement depends on your individual health and how low your B12 levels are

You need progressive strength work that tells your body, "We still need this tissue." For many people, that means lifting 2 to 4 times per week with basic movements: Squat or leg press pattern Hip hinge pattern Row Press Pulldown or pull-up variation Core work Carries or loaded movement Cardio can support health and calorie expenditure, but excessive cardio with low calories and low protein can make recovery harder

Check your iron and B12: Low levels of these nutrients can make cold sensitivity worse

Follow appropriate laboratory PPE and contamination-control procedures

The key constraint is consistency, not precision

In other words, Aetna may cover Zepbound again in the future