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When the layer of fat between the skin and the muscle is disrupted during the surgery, the scar is not able to move freely
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These properties contribute to a favorable pharmacokinetic profile and reduced off-target toxicities, which is anticipated to extend the therapeutic window
Conversely, the patient who took a 50mg dose will only have 25 mg in his system after the same amount of time, so it will take less time for the patient who took the lower dose to flush his system out of Diphenhydramine
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