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Neurologic aspects of cobalamin deficiency

All research applications are conducted in controlled laboratory settings using animal or in vitro models

Since D2HG and L2HG are indistinguishable in standard LC-MS, to determine which 2HG enantiomer(s) is affected, we adapted a chiral N-(p-toluenesulfonyl)-L-phenylalanyl chloride (TSPC) derivation followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis 24,40

If you need long-term storage, keep the vial lyophilized and reconstitute only what you will use inside the 28 day window

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Key Takeaway: The pairing of glutathione and collagen provides a comprehensive "shield and build" strategy for long-term cellular health and structural integrity