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Initial effects like improved sleep and recovery appear within 1-2 weeks

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Specific metabolic changes observed during GLP-1 treatment include: Improved insulin sensitivity , allowing cells to use glucose more efficiently Reduced hepatic glucose production , contributing to better glycaemic control Changes in body composition , with loss of both fat mass and some lean tissue Alterations in lipid metabolism , often resulting in improved cholesterol profiles Body composition studies suggest that lean tissue loss typically accounts for approximately 20-30% of total weight lost during GLP-1 therapy, though this varies considerably between individuals and depends on concurrent physical activity and protein intake

Large, greasy, spicy, or acidic dinners can worsen nighttime reflux or nausea

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The primary function of GLP-1 involves signaling the body to increase insulin production, thereby lowering blood sugar levels